October 3-5, 2018 was the Axons in the Hills meeting at the University of Heidelberg in Heidelberg, Germany co-organized by Maren Engelhardt, Maarten Kole, Andreas Draguhn, and Paul. This meeting brought together outstanding researchers from all over the world to talk about their recent findings on the study of axonal domains, like the axon initial segment and nodes of Ranvier in health and disease. Andrew presented his work on the effects of the ANK3 W1989R variant on forebrain connectivity and synchronization, with implications for bipolar disorder. René presented his poster on the effects of lithium on inhibitory signaling in the same mouse model. We had a great time seeing everyone and exploring the beautiful town of Heidelberg.